| 2021-08-06 20:00:116 augustus 2021 |   FC Marlène vs Scagha’66 | 14 - 0 | Waardergolf |
| 2021-08-13 20:30:1613 augustus 2021 |  RKAV Volendam vs FC Marlène | 3 - 5 | Opperdam |
| 2021-08-20 20:30:5620 augustus 2021 |  FC Marlène vs HV Veerhuys | 20:30:56Geannuleerd | Waardergolf |
| 2021-08-27 19:00:3127 augustus 2021 |  FC Marlène vs Texel’94 | 19:00:3119:00 | Waardergolf |
| 2021-09-10 21:30:0010 september 2021 |  FC Marlène vs AGOVV | 9 - 1 | Waardergolf |
| 2021-09-17 20:00:0017 september 2021 |  FC Eindhoven vs FC Marlène | 3 - 0 | Sportcentrum Eindhoven |
| 2021-09-24 21:30:0024 september 2021 |  FC Marlène vs White Stones | 9 - 4 | Waardergolf |
| 2021-10-01 21:30:041 oktober 2021 | FC Marlène vs AGOVV | 21:30:0421:30 | Waardergolf |
| 2021-10-03 16:00:003 oktober 2021 | RKAV Volendam vs FC Marlène | 3 - 3 | Opperdam |
| 2021-10-08 21:30:008 oktober 2021 | FC Marlène vs HV Veerhuys | 5 - 2 | Waardergolf |
| 2021-10-15 20:30:0015 oktober 2021 |  Leekster Eagles vs FC Marlène | 2 - 12 | Sportcentrum Leek |
| 2021-10-29 21:00:0029 oktober 2021 |  Tigers Roermond vs FC Marlène | 6 - 7 | Jo Gerrishal |
| 2021-11-05 21:30:005 november 2021 |  FC Marlène vs Groene Ster | 8 - 1 | Waardergolf |
| 2021-11-19 20:15:0719 november 2021 |  Hovocubo vs FC Marlène | 20:15:0720:15 | De Opgang |
| 2021-11-21 16:00:0021 november 2021 |  FC Marlène vs ZVV Den Haag | 15 - 4 | Waardergolf |
| 2021-11-26 20:30:0026 november 2021 |  Feyenoord Futsal vs FC Marlène | 4 - 8 | Topsportcentrum Rotterdam |
| 2021-12-03 20:30:003 december 2021 |  ASV Lebo vs FC Marlène | 6 - 5 | Sporthal Calvijn |
| 2021-12-10 20:30:0010 december 2021 | FC Marlène vs Hovocubo | 6 - 4 | Waardergolf |
| 2022-02-25 20:30:1425 februari 2022 |  FCK de Hommel vs FC Marlène | 5 - 6 | Maaspoort |
| 2022-03-06 18:00:256 maart 2022 | HV Veerhuys vs FC Marlène | 2 - 6 | Vredehof |
| 2022-03-11 20:30:1811 maart 2022 | FC Marlène vs RKAV Volendam | 8 - 3 | Waardergolf |
| 2022-03-18 20:00:1618 maart 2022 | FC Eindhoven vs FC Marlène | 5 - 4 | Sportcentrum Eindhoven |
| 2022-03-25 21:30:0625 maart 2022 |  FC Marlène vs Be’79 | 2 - 2 | Waardergolf |
| 2022-04-02 20:30:372 april 2022 | Hovocubo vs FC Marlène | 5 - 1 | De Opgang |
| 2022-04-08 21:30:288 april 2022 | FC Marlène vs ASV Lebo | 6 - 3 | Waardergolf |
| 2022-04-16 21:15:5716 april 2022 | ASV Lebo vs FC Marlène | 2 - 3 | Sporthal Calvijn |
| 2022-04-22 21:30:5722 april 2022 | FC Marlène vs FCK de Hommel | 7 - 2 | Waardergolf |
| 2022-04-24 16:00:0224 april 2022 | FC Marlène vs HV Veerhuys | 6 - 5 | Waardergolf |
| 2022-04-29 20:30:0629 april 2022 | RKAV Volendam vs FC Marlène | 2 - 4 | Opperdam |
| 2022-05-06 21:30:036 mei 2022 | FC Marlène vs FC Eindhoven | 5 - 4 | Waardergolf |
| 2022-05-08 18:00:318 mei 2022 | Be’79 vs FC Marlène | 18:00:3118:00 | |
| 2022-05-13 21:15:1013 mei 2022 | FC Marlène vs Hovocubo | 21:15:1021:15 | Waardergolf |
| 2022-05-20 21:30:1920 mei 2022 | Be’79 vs FC Marlène | 21:30:1921:30 | |
| 2022-05-22 16:00:5322 mei 2022 | FC Marlène vs Be’79 | 16:00:5316:00 | Waardergolf |
| 2022-05-27 20:45:1627 mei 2022 | FC Marlène vs Hovocubo | 20:45:1620:45 | Waardergolf |
| 2022-08-06 19:00:416 augustus 2022 |  FC Marlène vs HSV Panthers | 19:00:4119:00 | Waardergolf |
| 2022-08-15 19:30:0915 augustus 2022 | HV Veerhuys vs FC Marlène | 19:30:0919:30 | Vredehof |
| 2022-08-19 20:45:2819 augustus 2022 |  FC Marlène vs VNS United | 20:45:2820:45 | Waardergolf |
